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Loss of identity in immune cells explained

First author of the study Dr. Garima Garg (right) and Dr. Andreas Muschaweckh, two scientists of the Experimental Neurimmunology at TUM, are working with a flow cytometer (FACS, Fluorescence-Activated Cell Sorting). (Image: A. Eckert / TUM) Loss of identity in ...

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Testing pain relief treatments for whiplash

Researchers are keen to hear from people with neck pain from a whiplash injury following a car crash within the last three months Testing pain relief treatments for whiplash Researchers are investigating the effectiveness of non-opioid pain relief for people ...

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Brain pathways of aversion identified

Using optogenetics, the researchers were able to identify the identity of the nerve cells involved in aversion and map their interconnections. Photo: iStock Brain pathways of aversion identified What happens in the brain when we feel discomfort? Researchers at Karolinska ...

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Predicting sequence from structure

The binding interface between a peptide and its Bcl-2 protein target is composed of common structural motifs known as TERMs. Image: Sebastian Swanson and Avi Singer Predicting sequence from structure Researchers have devised a faster, more efficient way to design ...

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Tampering with the Brakes

Tampering with the Brakes UCSB neuroscientist Karen Szumlinski uncovers an unlikely ‘brake’ mechanism that helps to modulate overdrinking By Sonia Fernandez We’ve all seen these people. Maybe at one point in time we’ve actually been these people: messy, falling-down drunk, ...

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Why too much DNA repair can injure tissue

At left, photoreceptor cells of the retina have undergone severe damage after treatment with an alkylating agent. This damage is exacerbated by the DNA repair enzyme Aag. At right, photoreceptor cells lacking Aag appear normal following treatment with the alkylating ...

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This is a Neuron on Nicotine

In this image, a biosensor is targeted to a cell’s endoplasmic reticulum and glows green in the presence of nicotine Credit: Lester Group This is a Neuron on Nicotine Nicotine works inside cells to reinforce addiction When a person takes ...

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Gummy-like robots could help prevent disease

EPFL scientists have developed microscopic, hydrogel-based muscles that can manipulate and mechanically stimulate biological tissue. These soft, biocompatible robots could be used for targeted therapy and to help diagnose and prevent disease. Gummy-like robots could help prevent disease Human tissues ...

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