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دانلود رایگان کتاب , Biochemistry and Genetics

دانلود رایگان کتاب Biochemistry and Genetics

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This book provides over 130 disease examples (see Appendix) to illustrate the broad application of biochemistry and genetics to medicine. These include more common chromosomal or multifactorial disorders (Down syndrome, cleft palate, diabetes mellitus) that have incidences ranging from 1 in 200 to 1 in 2000–3000 to less common single gene disorders (cystic fibrosis, glycogen storage diseases) with incidences of 1 in 1600 to 1 per million individuals). Students can ignore clinical information about these rarer diseases since such knowledge is not tested in first/second-year biochemistry/genetic courses or USLME I examinations. The examples are provided to place basic science knowledge in clinical context and to
demonstrate the broad range of organ systems and medical specialties that are impacted by genetic/biochemical disease. More relevant to examination are much-used disease prototypes like diabetes, cleft palate, Down/Turner syndromes, sickle cell anemia, phenylketonuria (PKU): students may need to match them with underlying biochemical/genetic mechanisms.

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