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Preparing for a return of pox

Preparing for a return of pox by Bill Snyder Smallpox killed upwards of 500 million people in the 20th century before the virus was eradicated from the earth by large-scale vaccination campaigns. Close relatives in the poxvirus family, including cowpox ...

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Inside an Asthma Attack

Two kinds of imaging—optical coherence tomorgraphy and mechano-microscopy—reveal airway volume and thickness during an asthma attack (left) and an estimation of the force with which the airway muscle contracts. Image: Mass General Click for a full size image Inside an ...

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Imaging probe for retinal disease

Imaging probe for retinal disease by Leigh MacMillan In retinal diseases including age-related macular degeneration (AMD) and diabetic retinopathy, the growth of new blood vessels damages the retina and causes blindness. Inflammatory processes are thought to precede the blood vessel ...

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Understanding Signaling Pathways in Brain Tumors

Shi-Yuan Cheng, PhD, professor of Neurology, studies the role of microRNAs in proneural and mesenchymal brain tumor subtypes. Understanding Signaling Pathways in Brain Tumors BY SARAH PLUMRIDGE Northwestern Medicine scientists have shown how a signaling pathway and genetic material work ...

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Facing a Silent Liver Disease Epidemic

Micrograph of non-alcoholic fatty liver disease, demonstrating marked steatosis (fatty liver appears white). Credit: NEPHRON Wikimedia CC BY-SA 3.0 Facing a Silent Liver Disease Epidemic By Lisa M. Jarvis As nonalcoholic steatohepatitis, or NASH, stealthily becomes a leading cause of ...

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Early Detection to Beat Cancer

Early Detection to Beat Cancer Vadim Backman’s new screening technologies hold promise for dramatic changes in the diagnosis and treatment of cancer Northwestern Engineering’s Vadim Backman has developed a new suite of tools for cancer detection and diagnostics that could ...

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Rheumatoid subtypes explored by PheWAS

DNA computer – iStock Rheumatoid subtypes explored by PheWAS by Paul Govern A phenome-wide association study (PheWAS) is a computer-based method pioneered at Vanderbilt by Josh Denny, M.D., M.S., using de-identified DNA biobank data linked to health care billing codes. ...

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